Dermatology
Skin and mucosae frequently represent the first point of contact with pathogens and allergens, yet we still know relatively little of the role of the surface immune system in clearing such challenges. This is crucially important in understanding the mechanisms of skin diseases and related diseases, and for optimising approaches to cutaneous drug and vaccine delivery. The aim of Dr Graham Ogg's group is therefore to understand the role of human cutaneous T cells in mechanisms of disease, treatment and vaccination. They are investigating these questions through studies based on two common human diseases, atopic eczema and varicella zoster virus infection. As well as contributing to an understanding of disease pathogenesis, they aim to translate their findings to changes in clinical practice.
