Key publications
- Kawashima Y, Pfafferott K, Frater AJ, Matthews P, Payne R, Addo M et al Adapatation of HIV-1 to HLA I. Nature 2009 (in press).
- Dazert E, Neumann-Haefelin C, Bressanelli S, Fitzmaurice K, Kort J, Timm J, et al. Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response. J Clin Invest. 2009 Jan 12.
- Gaudieri S, Rauch A, Pfafferott K, Cheng W, McCaughan G, Shackel N et al Hepatitis C virus drug resistance and immune-driven adaptations: relevance to new anti-viral therapy. Hepatology 2009 (in press) (IF 10.4)
- Gallimore AM and Simon AK (2008) Positive and Negative influences of regulatory T cells on tumour immunity, Oncogene 27: 5886-93
- Salloum S, Oniangue-Ndza C, Neumann-Haefelin C, Hudson L, Giugliano S, aus dem Siepen M, et al. Escape from HLA-B*08-restricted CD8 T cells by hepatitis C virus is associated with fitness costs. J Virol. 2008 Dec;82(23):11803-12.
- Malavige GN, Seneviratne SL, Black A, Ogg G. Viral load, clinical disease severity and cellular immune responses in primary varicella zoster virus infection. PLOS ONE 2008;3:e3789.
- Wright CA, Edelmann M, Digleria K, Kollnberger S, Kramer H, McGowan S, McHugh K, Taylor S, Kessler BM, Bowness P. Ankylosing spondylitis monocytes show upregulation of proteins involved in inflammation and the Ubiquitin Proteasome pathway. Ann Rheum Dis. 2008 Oct 24. PMID: 18952638
- Ogg G. Role of T cells in the pathogenesis of atopic dermatitis. Clin Exp Allergy. 2008 Nov 19. [Epub ahead of print]
- Murphy RL, Autran B, Katlama C, Brucker G, Debre P, Calvez V, Clotet B, Clumeck N, Costagliola D, Deeks SG, Dorrell L, Gatell J, Haase A, Klein M, Lazzarin A, McMichael AJ, Papagno L, Schacker TW, Wain-Hobson S, Walker BD, Youle M. A step ahead on the HIV collaboratory. Science. 2009 Jun 5;324(5932):1264-5
- Yang H, Guimarães-Walker A, Hibbs S, Dong T, Stacey A, Borrow P, Hanke T, Davenport MP, McMichael A, Dorrell L. Interleukin-10 responses to therapeutic vaccination during HAART and after analytical therapy interruption. AIDS 2009, in press.
- Dorrell L, Williams P, Suttill A, Brown D, Roberts J, Conlon C, Hanke T, McMichael A.Safety and tolerability of recombinant modified vaccinia virus Ankara expressing an HIV-1 gag/multiepitope immunogen (MVA.HIVA) in HIV-1-infected persons receiving combination antiretroviral therapy. Vaccine. 2007 Apr 30;25(17):3277-83. Epub 2007 Jan 11.
- Yang H, Dong T, Turnbull E, Ranasinghe S, Ondondo B, Goonetilleke N, Winstone N, di Gleria K, Bowness P, Conlon C, Borrow P, Hanke T, McMichael A, Dorrell L.
- Broad TCR usage in functional HIV-1-specific CD8+ T cell expansions driven by vaccination during highly active antiretroviral therapy. J Immunol. 2007 Jul 1;179(1):597-606.
- Létourneau S, Im EJ, Mashishi T, Brereton C, Bridgeman A, Yang H, Dorrell L, Dong T, Korber B, McMichael AJ, Hanke T.Design and pre-clinical evaluation of a universal HIV-1 vaccine. PLoS ONE. 2007 Oct 3;2(10):e984.
- Ondondo BO, Rowland-Jones SL, Dorrell L, Peterson K, Cotten M, Whittle H, Jaye A.Comprehensive analysis of HIV Gag-specific IFN-gamma response in HIV-1- and HIV-2-infected asymptomatic patients from a clinical cohort in The Gambia. Eur J Immunol. 2008 Dec;38(12):3549-60.
- Li CK, Wu H, Yan H, Ma S, Wang L, Zhang M, Tang X, Temperton NJ, Weiss RA, Brenchley JM, Douek DC, Mongkolsapaya J, Tran BH, Lin CL, Screaton GR, Hou JL, McMichael AJ, Xu XN.T cell responses to whole SARS coronavirus in humans. J Immunol. 2008 Oct 15;181(8):5490-500.
- Lee LY, Ha do LA, Simmons C, de Jong MD, Chau NV, Schumacher R, Peng YC, McMichael AJ, Farrar JJ, Smith GL, Townsend AR, Askonas BA, Rowland-Jones S, Dong T.Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals. J Clin Invest. 2008 Oct;118(10):3478-90.
- Armitage AE, McMichael AJ, Drakesmith H.Reflecting on a quarter century of HIV research. Nat Immunol. 2008 Aug;9(8):823-6. No abstract available.
- Armitage AE, Katzourakis A, de Oliveira T, Welch JJ, Belshaw R, Bishop KN, Kramer B, McMichael AJ, Rambaut A, Iversen AK.Conserved footprints of APOBEC3G on Hypermutated human immunodeficiency virus type 1 and human endogenous retrovirus HERV-K(HML2) sequences. J Virol. 2008 Sep;82(17):8743-61. Epub 2008 Jun 18.
- Ho LP, Denney L, Luhn K, Teoh D, Clelland C, McMichael AJ. Activation of invariant NKT cells enhances the innate immune response and improves the disease course in influenza A virus infection. Eur J Immunol. 2008 Jul;38(7):1913-22.
- Ishizuka J, Stewart-Jones GB, van der Merwe A, Bell JI, McMichael AJ, Jones EY.The structural dynamics and energetics of an immunodominant T cell receptor are programmed by its Vbeta domain. Immunity. 2008 Feb;28(2):171-82.
- Duvall MG, Precopio ML, Ambrozak DA, Jaye A, McMichael AJ, Whittle HC, Roederer M, Rowland-Jones SL, Koup RA.Polyfunctional T cell responses are a hallmark of HIV-2 infection. Eur J Immunol. 2008 Feb;38(2):350-63.
- Li D, Chen N, McMichael AJ, Screaton GR, Xu XN. Generation and characterisation of CD1d tetramer produced by a lentiviral expression system. J Immunol Methods. 2008 Jan 31;330(1-2):57-63. Epub 2007 Nov 26.
- Duvall MG, Loré K, Blaak H, Ambrozak DA, Adams WC, Santos K, Geldmacher C, Mascola JR, McMichael AJ, Jaye A, Whittle HC, Rowland-Jones SL, Koup RA.Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection. J Virol. 2007 Dec;81(24):13486-98. Epub 2007 Oct 3.
- Schneidewind A, Brockman MA, Yang R, Adam RI, Li B, Le Gall S, Rinaldo CR, Craggs SL, Allgaier RL, Power KA, Kuntzen T, Tung CS, LaBute MX, Mueller SM, Harrer T, McMichael AJ, Goulder PJ, Aiken C, Brander C, Kelleher AD, Allen TM.Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication. J Virol. 2007 Nov;81(22):12382-93. Epub 2007 Sep 5.
- Fellay J, Shianna KV, Ge D, Colombo S, Ledergerber B, Weale M, Zhang K, Gumbs C, Castagna A, Cossarizza A, Cozzi-Lepri A, De Luca A, Easterbrook P, Francioli P, Mallal S, Martinez-Picado J, Miro JM, Obel N, Smith JP, Wyniger J, Descombes P, Antonarakis SE, Letvin NL, McMichael AJ, Haynes BF, Telenti A, Goldstein DB.A whole-genome association study of major determinants for host control of HIV-1. Science. 2007 Aug 17;317(5840):944-7. Epub 2007 Jul 19.
- Cox JH, McMichael AJ, Screaton GR, Xu XN.CTLs target Th cells that acquire bystander MHC class I-peptide complex from APCs. J Immunol. 2007 Jul 15;179(2):830-6.
- Lühn K, Simmons CP, Moran E, Dung NT, Chau TN, Quyen NT, Thao le TT, Van Ngoc T, Dung NM, Wills B, Farrar J, McMichael AJ, Dong T, Rowland-Jones S.Increased frequencies of CD4+ CD25(high) regulatory T cells in acute dengue infection. J Exp Med. 2007 May 14;204(5):979-85. Epub 2007 Apr 23.
- Lambe T, Simpson RJ, Dawson S, Bouriez-Jones T, Crockford TL, Lepherd M, Latunde-Dada GO, Robinson H, Raja KB, Campagna DR, Villarreal G Jr, Ellory JC, Goodnow CC, Fleming MD, McKie AT, Cornall RJ.Identification of a Steap3 endosomal targeting motif essential for normal iron metabolism. Blood. 2008 Oct 27. [Epub ahead of print]
- Lau AW, Biester S, Cornall RJ, Forrester JV.Lipopolysaccharide-activated IL-10-secreting dendritic cells suppress experimental autoimmune uveoretinitis by MHCII-dependent activation of CD62L-expressing regulatory T cells. J Immunol. 2008 Mar 15;180(6):3889-99.
- Heazlewood CK, Cook MC, Eri R, Price GR, Tauro SB, Taupin D, Thornton DJ, Png CW, Crockford TL, Cornall RJ, Adams R, Kato M, Nelms KA, Hong NA, Florin TH, Goodnow CC, McGuckin MA. Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis. PLoS Med. 2008 Mar 4;5(3):e54.
- Silver KL, Crockford TL, Bouriez-Jones T, Milling S, Lambe T, Cornall RJ.MyD88-dependent autoimmune disease in Lyn-deficient mice. Eur J Immunol. 2007 Oct;37(10):2734-43.
- Nijnik A, Woodbine L, Marchetti C, Dawson S, Lambe T, Liu C, Rodrigues NP, Crockford TL, Cabuy E, Vindigni A, Enver T, Bell JI, Slijepcevic P, Goodnow CC, Jeggo PA, Cornall RJ. DNA repair is limiting for haematopoietic stem cells during ageing. Nature. 2007 Jun 7;447(7145):686-90.
- Strickland GT, El-Kamary SS, Klenerman P, Nicosia A. Hepatitis C vaccine: supply and demand. Lancet Infect Dis. 2008 Jun;8(6):379-86.
- Klenerman P, Kim A. HCV-HIV coinfection: simple messages from a complex disease. PLoS Med. 2007 Oct 9;4(10):e240. Review. No abstract available.
