Pneumococcal vaccines
Provisional results from an ongoing study in 348 individuals of the use of the infant pneumococcal conjugate vaccine in older adults has demonstrated that this vaccine induced immunologic memory in contrast to the currently recommended plain polysaccharide vaccine. Furthermore, participants who received the currently recommended vaccine had a poorer response to a dose of the infant vaccine than those who had no prior immunisation, probably as a result of B cell memory depletion. These data support the use of conjugate polysaccharide vaccines in adults over the current recommendation of a plain polysaccharide vaccine.
